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Following a median follow-up of 2.1 years, the risk of suffering a major cardiovascular adverse event (death, nonfatal AMI, nonfatal stroke or hospitalization for unstable angina) was similar in both the lixisenatide and the placebo arms (HR 1.02

Effectiveness depends on which of the available drugs are taken, with tirzepatide seeing higher weight loss than semaglutide and older GLP-1s

& Sharman, T.(2024)

[PMID: 36617205] PubMed record related to this compound for laboratory literature review

Appetite suppression can make it challenging to consume the quantities of protein required to maintain muscle, particularly over months of treatment